Efficacy may be determined by clinical trial or by modeling , and cost -
effectiveness may be evaluated in parallel with clinical efficacy . Model of Clinical
Efficacy Following the introduction of whole - body PET imaging in the early
1990s , it ...
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Handbook of Medical Psychiatry
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Clinical. Pharmacology. Trials. Ajay Verma, Ruben Declercq, Alexandre Coimbra
, and Eric Achten The Use of fMRI in Decision-Making ... pharmacodynamics,
proof of mechanism, proof of concept, and even proof of clinical efficacy (
Hargreaves 2008; Wong et al. 2009). Positron emission tomography (PET) with
radiolabeled ligands is already well incorporated into clinical pharmacology for
determining ...