In calling this book Cocaine Changes , we are referring to more than the changes in our views of cocaine . The number and types of people using cocaine have changed , as has the mode of ingestion employed by many of them .
Author: Dan Waldorf
Publisher: Temple University Press
"In an arena of public policy where misinformation and disinformation reigns, ... facts are desperately needed, and Cocaine Changes gives us a bucketful of them. Anyone who values rationality and is concerned about the harmful efforts of our misbegotten drug policy should read this book." ?Ira Glasser, Executive Director, ACLU"I know of no other book that offers so much information on the subject so clearly and calmly presented. For anyone interested in the natural history of cocaine use in America now, Cocaine Changes provides the best, most comprehensive available resource." ?Lester Grinspoon, M.D., Harvard Medical School "This book puts the cocaine scare of the 1980s to the test and places cocaine in a more realistic perspective. By examining the lives of hundreds of heavy users, it discovers that even among this group, cocaine use is not always cocaine abuse." ?Kevin B. Zeese, Drug Policy Foundation "This provocative study challenges many of the prevailing myths about cocaine and crack use, and is essential reading for any researchers, educators, policymakers, law enforcement personnel, or concerned citizens who wish to make informed judgments." ?Patricia G. Erickson, Ph.D., Head, Drug Policy Research Program (Canada) "This book puts the cocaine scare of the 1980s to the test and places cocaine in a more realistic perspective. By examining the lives of hundreds of heavy users, it discovers that even among this group, cocaine use is not always cocaine abuse." ?Kevin B. Zeese, Vice-President and Counsel, Drug Policy Foundation
KRAKKA UNIVERSITY OF CALIFORNIA , SAN DIEGO Cocaine abusers don't exist in a vacuum . ... This pamphlet addresses the questions and concerns that arise when cocaine affects someone you love and suggests places to turn for help .
Release on 2014-03-28 | by Frances R. Frankenburg MD
Cocaine hydrochloride is changed from a salt into a base by removing the hydrochloride molecule.23 This is done by using any number of products, such as ammonia. Cocaine and ammonia seem like an unlikely combination, but it was widely ...
Author: Frances R. Frankenburg MD
Category: Health & Fitness
A psychiatrist examines how the world's four most important mind-altering substances— alcohol, cocaine, nicotine, and opiates—have played a significant role throughout human history, and explains how these powerful drugs affect the brain and cause addiction. • Presents a historical review of four plant-derived drugs—alcohol, cocaine, nicotine, and opiates—and their effects throughout human civilization, as well as a fascinating exploration of the mystery and misery of addiction • Provides comprehensive explanations of medical and psychiatric effects of these drugs • Supplies stories of people who made discoveries about these drugs or who had their lives altered by them • Describes the discovery of the way in which the brain works • Includes illustrations of brain pathways and of the four plants of origin for these drugs, and maps showing drug trade triangles
One small study examined cocaine - induced sleep EEG changes in depressed patients . Modest doses of cocaine ( 30 to 200 mg daily ) given orally for ten days suppressed rapid eye movement sleep . When cocaine was stopped , a rebound of ...
The proliferation ofcfos proteins may help to explain how cocaine cantrigger changes inthe neurons' genetic expression, the redefinition of the chemical environment as normal, thenumber of receptors, and the powerful and longlasting ...
Author: Mark S. Gold
Publisher: Springer Science & Business Media
For every news story in the popular press detailing the horrors and the violence associated with cocaine, there have been corresponding studies in the medical litera ture shedding new light on our understanding of this most troublesome drug. Our knowledge of addiction, and specifically cocaine addiction, has increased dra matically within the last few years. We stand on the threshold of an exciting new era in addictionology that promises better treatments, improved diagnostic proce dures, and more effective preventative strategies. We must prepare today for the avalanche of exciting dis coveries that will arrive in the coming years. Along with the first two volumes in this series, Marijuana and Alcohol, this book strives to help the general medical community to stay abreast of the latest medical information on addiction, while presenting a fundamental resource on the neurobiology, physiology, epidemiology, history, diagnosis, treatment, and p- v vi PREFACE vention of cocaine abuse. In addition, the comorbidity of cocaine abuse and eating disorders, depression, anx iety, hypertension, and various other disorders is dis cussed in detail. Finally, the last chapter presents new strategies tailored to specific patient groups and aimed at confronting the ever-changing face of drug abuse.
If to Kroller is due the discovery of the an- In the closed eye no changes whatever took aesthetic property of Cocaine , it was re- place in the appearance of the cornea . In served for Corning to utilize the great discov- the other eye ...
The administration of high-dose cocaine (5 mg/kg) intravenously to dogs produces negative inotropic and potent type I ... myocardial ischemia during the first few weeks of withdrawal, but the mechanism for these changes is unclear.
Author: Donald G. Barceloux
Publisher: John Wiley & Sons
This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.
By MEDICAL PROGRESS . dropping distilled water upon the cornea , between the applications of the cocaine , changes which had already occurred were not removed , but their increase ON LESIONS OF THE Cornea FOLLOWING THE IN- was prevented ...
Release on 1988 | by College on Problems of Drug Dependence (U.S.). Scientific Meeting
The changes in BZD receptors labelled with [ 3 ] RO 15-1788 were not attributable to changes in the binding affinity of the receptors since there were no significant differences in Kd values for tissue derived from saline- and cocaine ...
Author: College on Problems of Drug Dependence (U.S.). Scientific Meeting
... since cocaine - induced changes in sensitivity to apomorphine , as well as apomorphine - induced climbing behavior in cocaine - treated mice , were both inhibited by naloxone . 2373-3N16 Lead - induced changes in NMDA receptor ...
We could warn against In order to ascertain how far the changes the perfidy of the gaudy foxglove and the in the corneal ... ON LESIONS OF THE CORNEA FOLLOW- changes were noticed ; these increased , and , ING THE INSTILLATION OF COCAINE ...
Perceived risk peaked around 1990 or 1991 , and then decreased slightly until 1995 , when a significant decline in perceived risk of trying cocaine occurred . There has been little further change since then . Trends in attitudes toward ...
In the other eye , after three or four minutes , slight changes were noticed ; these increased , and , in twenty to twenty - five minutes after the cocaine had been commenced , the cornea presented a superficial ...
Release on 1995 | by College on Problems of Drug Dependance (U.S.). Scientific Meeting
This study investigated pre - to posttreatment changes in level of consumption using an empirical , descriptive approach ... The cocaine use reduction variable had four possible values : no change in level of use and one , two or three ...
Author: College on Problems of Drug Dependance (U.S.). Scientific Meeting
Among the multiple levels of analysis in the neuradaptations that occur in response to drugs of abuse are changes in structural plasticity ... the extent and direction of change vary with time following last exposure to chronic cocaine, ...
Author: Shafiqur Rahman
Publisher: Academic Press
The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain. * Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields
Release on 2014-12-02 | by Jean-Pierre Bourguignon
duration of cocaine use, drug quality, route of administration, periods of abstinence and total lifetime intake) and in ... Previous studies have used this approach to investigate cocaine-related changes in receptor distribution (Wolf ...
Author: Jean-Pierre Bourguignon
This volume provides the reader with a pathophysiological perspective on the role of CNS in puberty and adolescence, starting from genetic/molecular aspects, going through structural/imaging changes and leading to physical/behavioral characteristics. Therefore, renowned investigators involved in both animal and human research shared recent data as well as overall appraisal of relevant questions around CNS control of puberty and adolescence. No doubt that this volume will inspire those involved in either scientific research or clinical practice or both in the fascinating field of puberty and adolescence.
'Excitatory synapses on dopamine (DA) neurons in the ventral tegmental area (VTA) are modulated following exposure to various addictive drugs, including cocaine. Previously we have shown that cocaine affects GABA(A) receptor ...
Catecholamines—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Catecholamines in a concise format. The editors have built Catecholamines—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Catecholamines in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Catecholamines—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Changes occur in the entire configuration of one's thinking ability when taking cocaine. Cocaine affects the part of the brain that has to do with love and sex. It also gives many people paranoid hallucinations.
Author: SHARON TETILA COX
Publisher: Xlibris Corporation
Category: Literary Criticism
The stories in this book are about ordinary everyday human beings as we are each challenged and often socially seduced biologically, psycho-socially, spiritually, and economically as biopsychosocial and spiritual beings. These are also riveting true stories of the biopsychosocial and spiritual being who demonstrates the courage to stand strong during challenges of social seduction not just for oneself, but also for others. Many of us muster up the courage to do the things that are right according to our spiritual faith which for me includes my Christian ethics meaning even when we do not necessarily feel like doing them. We find the courage to not do the things we’re being hedonistically enticed or seduced into doing when we know it’s not morally right, or against our practicing spiritual ethics which clearly tells us not to do them. While many biopsychosocial and spiritual beings pray, some chant, others meditate, study/tarry, etc. Often this is based upon our individually unique beliefs and practices we are allowed here in America. My Christian Ethics however are rooted in the Science of Biblical Hermeneutics which truly empowers me with full armor and the sword of the spirit that sustains and keeps me steady allowing me to maintain my inner peace in the midst of storms including the ones shared in this book.
and parietal lobes, even though they have no changes in neuropsychologic function (325). However, other groups have ... (332) found that similar abnormalities were found in ADC patients and in chronic cocaine and polydrug abusers.
Author: Martin P. Sandler
Publisher: Lippincott Williams & Wilkins
The gold standard text-reference Diagnostic Nuclear Medicine is now in its Fourth Edition--with a sharp clinical focus, a streamlined new single-volume format, and a very attractive price. Written by the top authorities in the specialty, this brand-new edition offers encyclopedic coverage of clinically relevant developments in nuclear medicine--including instrumentation, radiopharmaceuticals, and applications. Readers will find the latest on PET, molecular imaging, SPECT myocardial perfusion imaging, monoclonal antibody therapy, and the use of functional imaging studies in oncology. This edition has been trimmed from two volumes to one, so that readers can find exactly what they need quickly, without cross-checking between volumes.
Another source of cocaine fatalities comes from the changes that occur in the heartbeat as the electrical signal between the brain and the heart becomes distorted . As the heartbeat speeds up above its normal rate , the heart may skip ...