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Human Genes and Genomes

Author: Leon E. Rosenberg
Publisher: Academic Press
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In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor's office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more Explores ethical, legal, regulatory and economic aspects of genomics in medicine. Integrates historical (classical) genetics approach with the latest discoveries in structural and functional genomics


The Human Genome

Author: Julia E. Richards
Publisher: Academic Press
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Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome,2E includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information . Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students Full, 4-color illustration program enhances and reinforces key concepts and themes Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers


Pediatric Epidemiology

Author: W. Kiess
Publisher: Karger Medical and Scientific Publishers
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Pediatric epidemiology differs substantially from general epidemiology especially when it comes to ethical, developmental and societal aspects. This unique book addresses biological considerations and ethical and legal questions in dealing with pediatric and adolescent populations. Classic topics, such as how to recruit representative samples, how to deal with confounding variables, and how to work with genetic information are the core areas of the book are also in focus. Last but not the least, this volume adds to the current understanding of global trends in occurrence, transmission, and control of epidemic pediatric diseases. This book not only serves as a textbook for epidemiologists, pediatricians, geneticists, and child and public health specialists but is also a key reference for those embarking on pediatric cohort studies and epidemiological studies involving the pediatric population.


Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2004

Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
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The Value of Genetic and Genomic Technologies

Author: Institute of Medicine
Publisher: National Academies Press
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Knowing one's genetic disposition to a variety of diseases, including common chronic diseases, can benefit both the individual and society at large. The IOM's Roundtable on Translating Genomic-Based Research for Health held a workshop on March 22, 2010, to bring together diverse perspectives on the value of genetic testing, and to discuss its use in clinical practice.


Genetics Primer for Exercise Science and Health

Author: Stephen M. Roth
Publisher: Human Kinetics
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Genetics Primer for Exercise Science and Healthis the first text dedicated to the basic concepts of genetics in relation to the broad range of topics in exercise science and health. Author Stephen M. Roth, PhD, makes the content comprehensible for readers who are unfamiliar with genetics without sacrificing the foundational and critical understanding necessary for interpreting research findings and incorporating genetics into research programs. Genetics Primer for Exercise Science and Healthmaintains a practical focus and addresses common concerns when preparing to study genetics, such as how to use online search tools to identify existing research literature and how to identify and select candidate genes using genome databases. Through this text, readers will discover these concepts: -The basics of DNA and genetics as they relate to health, physical activity, and sport -Specific skills and strategies for interpreting and applying genetics findings in research -How genetics research may affect sport performance training and clinical practice -The ethical issues raised by genetics in society and sport Special focus sections are incorporated throughout the text, providing expanded discussions of interesting topics in each chapter. Students see examples of how the principles described in the book have played out in real-life research, and they receive explicit instructions on planning and interpreting genetics research. Pedagogical aids such as summaries, key terms, and review questions also make this text ideal for efficient learning. Part Ipresents readers with the basic biology and genetics information they need in order to understand and apply the information to exercise science. Part IIexplores the research and design methods that will help readers interpret and apply their findings. Part IIIaddresses some of the current research findings in the area of genetics in exercise and health and discusses current issues in the field, including the potential for misuse of new genetic technologies and the ethics involved in gene doping. Genetics Primer for Exercise Science and Healthis the second volume in Human Kinetics' Primers in Exercise Science Series, which provides students and professionals with a nonintimidating basic understanding of the science behind its topic and, where appropriate, how that science is applied. These books are written by leading researchers and teachers in their respective areas of expertise. The authors present in an easy-to-understand manner the essential concepts in dynamic, complex areas of scientific knowledge. The books in the series are ideal for researchers and professionals who need some background in an unfamiliar scientific area. The books also function as accessible basic references for those who will be returning to the material often. This particular book adds a health dimension to the exercise science focus of the series, with discussions on disease- and health-related information. Genetic research will play an important role in the future practice of exercise science and health, requiring students and professionals to have this basic knowledge for success in their careers. Through its practical presentation of current and basic topics, Genetics Primer for Exercise Science and Healthmakes the case for more universities to introduce genetics courses to their curricula. Having the essential topics of genetics in a single, practical introductory text will facilitate the work of instructors, students, and professionals.


Public Health Nursing E Book

Author: Marcia Stanhope
Publisher: Elsevier Health Sciences
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Now in its 8th edition, the "gold standard" in community health nursing provides comprehensive and up-to-date content to keep you at the forefront of the ever-changing community health climate and prepare you for an effective nursing career. In addition to a solid foundation in concepts and interventions for individuals, families, and communities, you will find real-life applications of the public nurse's role, Healthy People 2020 initiatives, new chapters on forensics and genomics, plus timely coverage of disaster management and important client populations such as pregnant teens, the homeless, immigrants, and more. Evidence-Based Practice boxes illustrate how the latest research findings apply to public/community health nursing. Separate chapters on disease outbreak investigation and disaster management describe the nurse's role in surveilling public health and managing these types of threats to public health. Separate unit on the public/community health nurse's role describes the different roles and functions of the public/community health nurse within the community. Levels of Prevention boxes show how community/public health nurses deliver health care interventions at the primary, secondary, and tertiary levels of prevention. What Do You Think?, Did You Know?, and How To? boxes use practical examples and critical thinking exercises to illustrate chapter content. The Cutting Edge highlights significant issues and new approaches to community-oriented nursing practice. Practice Application provides case studies with critical thinking questions. Separate chapters on community health initiatives thoroughly describe different approaches to promoting health among populations. Appendixes offer additional resources and key information, such as screening and assessment tools and clinical practice guidelines. Linking Content to Practice boxes provide real-life applications for chapter content. NEW! Healthy People 2020 feature boxes highlight the goals and objectives for promoting health and wellness over the next decade. NEW! The Nurse in Forensics chapter focuses on the unique role of forensic nurses in public health and safety, interpersonal violence, mass violence, and disasters. NEW! Genomics in Public Health Nursing chapter includes a history of genetics and genomics and their impact on public/community health nursing care.


The Economics of Genomic Medicine

Author: Institute of Medicine
Publisher: National Academies Press
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The sequencing of the human genome and the identification of links between specific genetic variants and diseases have led to tremendous excitement over the potential of genomics to direct patient treatment toward more effective or less harmful interventions. Still, the use of whole genome sequencing challenges the traditional model of medical care where a test is ordered only when there is a clear indication for its use and a path for downstream clinical action is known. This has created a tension between experts who contend that using this information is premature and those who believe that having such information will empower health care providers and patients to make proactive decisions regarding lifestyle and treatment options. In addition, some stakeholders are concerned that genomic technologies will add costs to the health care system without providing commensurate benefits, and others think that health care costs could be reduced by identifying unnecessary or ineffective treatments. Economic models are frequently used to anticipate the costs and benefits of new health care technologies, policies, and regulations. Economic studies also have been used to examine much more specific issues, such as comparing the outcomes and cost effectiveness of two different drug treatments for the same condition. These kinds of analyses offer more than just predictions of future health care costs. They provide information that is valuable when implementing and using new technologies. Unfortunately, however, these economic assessments are often limited by a lack of data on which to base the examination. This particularly affects health economics, which includes many factors for which current methods are inadequate for assessing, such as personal utility, social utility, and patient preference. To understand better the health economic issues that may arise in the course of integrating genomic data into health care, the Roundtable on Translating Genomic-Based Research for Health hosted a workshop in Washington, DC, on July 17-18, 2012, that brought together economists, regulators, payers, biomedical researchers, patients, providers, and other stakeholders to discuss the many factors that may influence this implementation. The workshop was one of a series that the roundtable has held on this topic, but it was the first focused specifically on economic issues. The Economics of Genomic Medicine summarizes this workshop.


The Human Genome Project and the Future of Health Care

Author: Thomas H. Murray
Publisher: Indiana University Press
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"The volume deserves our serious attention. The authors have provided us an invaluable primer about the HGP and its implications for the future of American health care." -- Jurimetrics "This book does make a real contribution... in explaining why the genetics revolution holds so much promise and why it is so difficult to bring that promise to fruition." -- The Journal of Legal Medicine "... marked by a forward-looking, analytically and empirically grounded thematic coherence. The editors' carefully crafted template and contributions successfully focus and organize the material." -- Annals of Internal Medicine "Excellent" -- Canadian Medical Association Journal "The editors have done a very good job integrating the contents into a very useful and readable information source." -- Choice "... this highly focused book is a well-written, thoughtful, and insightful consideration of the HGP and is valuable reading for anyone concerned with the future of our country's medical infrastructure." -- Science Books & Films (**Highly recommended) "A distinguished group of scientists, lawyers, and scholars have written a coherent, readable account of the legal, medical, ethical, and policy issues many (if not all) of us will be wrestling with on both a personal and a public level, as a result of current genetic research." -- Library Journal "Each of the contributors is a distinguished authority on the topic. Ethicists, especially, will find well-developed presentation of issues, with exposition of the differing ethical assumptions in tension in the society debate." -- Doody's Health Sciences Book Review Home Page How will the science of gene mapping and gene manipulation affect health care? Leading scholars explore the clinical, ethical, legal, and policy implications of the Human Genome Project for the forms of health care, who delivers it, who receives it, and who pays for it.


Epigenetics and Human Health

Author: Alexander Haslberger
Publisher: John Wiley & Sons
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After first introducing the concept of epigenetics, this handbook and ready reference provides an overview of the main research on epigenetics. It adopts a multidisciplinary approach, involving molecular biology, molecular epidemiology and nutritional science, with a special focus of the book is on disease prevention and treatment. Of interest to all healthcare-related professionals as well as nutritionists, and the medical community focusing on disease prevention.