Within this study we explored whether OLE can attenuate SAA-driven responses in HCAEC. MethodsHCAEC were treated with SAA (1000nM) and/or OLE (0.5 and 1mg/ml).
BackgroundOlive leaf extract (OLE) is used in traditional medicine as a food supplement and as an over-the-counter drug for a variety of its effects, including anti-inflammatory and anti-atherosclerotic ones. Mechanisms through which OLE could modulate these pathways in human vasculature remain largely unknown. Serum amyloid A (SAA) plays a causal role in atherosclerosis and cardiovascular diseases and induces pro-inflammatory and pro-adhesive responses in human coronary artery endothelial cells (HCAEC). Within this study we explored whether OLE can attenuate SAA-driven responses in HCAEC. MethodsHCAEC were treated with SAA (1000nM) and/or OLE (0.5 and 1mg/ml). The expression of adhesion molecules VCAM-1 and E-selectin, matrix metalloproteinases (MMP2 and MMP9) and miRs 146a, let-7e and let-7g (involved in the regulation of inflammation) was determined by qPCR. The amount of secreted IL-6, IL-8, MIF and GRO-u03b1 in cell culture supernatants was quantified by ELISA. Phosphorylation of NF-u03baB was assessed by Western blot and DNA damage was measured using the COMET assay. ResultsOLE decreased significantly released protein levels of IL-6 and IL-8, as well as mRNA expression of E-selectin in SAA-stimulated HCAEC and reduced MMP2 levels in unstimulated cells. Phosphorylation of NF-u03baB (p65) was upregulated in the presence of SAA, with OLE significantly attenuating this SAA-induced effect. OLE stabilized SAA-induced upregulation of microRNA-146a and let-7e in HCAEC, suggesting that OLE could fine-tune the SAA-driven activity of NF-u03baB by changing the microRNA networks in HCAEC. SAA induced DNA damage and worsened the oxidative DNA damage in HCAEC, whereas OLE protected HCAEC from SAA- and H2O2-driven DNA damage. ConclusionOLE significantly attenuated certain pro-inflammatory and pro-adhesive responses and decreased DNA damage in HCAEC upon stimulation with SAA. The reversal of SAA-driven endothelial activation by OLE might contribute to its anti-inflammatory and anti-atherogenic effects in HCAEC.
Study was carried out to investigate the adsorption characteristics of olive leaf extract on the macroporous adsorption resins and the efficiency of the adsorption column for the separation and purification of oleuropein and rutin from the ...
Author: Alihan Karakaya
Study was carried out to investigate the adsorption characteristics of olive leaf extract on the macroporous adsorption resins and the efficiency of the adsorption column for the separation and purification of oleuropein and rutin from the crude plant extract. Both static and dynamic experiments were performed. In static studies, the performances of three macroporous Amberlite resins namely XAD4, XAD 16 and XAD7HP for the adsorption of polyphenols were evaluated. XAD7HP was chosen as an adsorbent for further adsorption study. XAD7HP was selected for the studies of isotherms, kinetics of adsorption. In conventional alcohol extraction, crude feedstock is mixed with solvent which is alcohol for most cases, and then extract is distilled to remove ethanol. This process ends with a certain amount of residual ethanol because of complication in separation process for ethanol and water makes an azeotropic binary system. The results showed that adsorption capacity of an alcoholic solution with 10 % ethanol content is better than aqueous solution which contained no ethanol. In dynamic studies, the adsorption and desorption experiments were carried out on a glass column packed with XAD7HP resin. The flow velocity 122 cm/h operated as a fixed bed while operation was in an expanded bed mode at 367 cm/h and 611 cm/h, respectively. The effectiveness of the packed bed adsorption and the fluidized bed adsorption were compared. The results show the breakthrough occurred earlier when the feed flow velocity increased. In the elution step, elution program with 2,000 ml for 0 %, 4,000 ml for 40 % and 3,000 ml for 90 % aqueous ethanol was used to achieve an efficient separation. Total phenol content and antioxidant capacity of olive leaf crude extract and effluent fractions were analyzed in order to find the difference between before and after separation. Consequently, fluidized bed adsorption is a promising alternative for the packed bed adsorption in order to isolate oleuropein and rutin from the olive leaf extract.
Mix the latest scientific data on herbal products and physical ailments with the need for natural approaches to health, and what do you have? The Woodland Health Series.
Author: Jack Ritchason
Publisher: Woodland Publishing
Category: Health & Fitness
Mix the latest scientific data on herbal products and physical ailments with the need for natural approaches to health, and what do you have? The Woodland Health Series. Each of these booklets gives concise, pertinent information for those looking to nature for optimal health.
Olive leaf extract is derived from the leaves of the olive plant, a medicinal herb used therapeutically for centuries.
Author: Lori Barrett
Publisher: Healthy Living Publications
Category: Health & Fitness
Olive leaf extract is derived from the leaves of the olive plant, a medicinal herb used therapeutically for centuries. Scientists have found that oleuropein, the active compound in olive leaf extract, can effectively lower bad cholesterol and blood pressure and fight disease-causing microorganisms, such as bacteria, fungi, viruses, and protozoa. Cancer, diabetes, heart disease, inflammation, are among the diseases that have responded to treatment. In addition, the extract can be used topically to combat eczema and acne, reduce skin damage caused by UVB radiation and hydrate dry skin. In addition to discovering all of the health-promoting benefits of olive leaf extract, you'll receive expert advice on the available forms of olive leaves (capsules, tinctures, powders, and teas) and how to determine which ones are best suited to meet your needs.
Details a compouond taken from Olive leves called Oleurupein that has disease resistant properties and that is effective in treating such afflictions as HIV, influenza, sore throats, pneumonia, infections and much more, in an informative ...
Author: Morton Walker
Publisher: Kensington Books
Category: Health & Fitness
Details a compouond taken from Olive leves called Oleurupein that has disease resistant properties and that is effective in treating such afflictions as HIV, influenza, sore throats, pneumonia, infections and much more, in an informative natural guide to healing. Original. 5 star average customer rating on Amazon.
Such olive leaf ingredients are now available as a single extract processed into a supplement. Because the olive leaf is merely a bitter-tasting vegetable able to be
brewed as a green tea, or eaten in green salad, ingesting it is absolutely safe.
Reaching nearly 1 million readers monthly, Better Nutrition celebrates 70 years as a leading in-store distributed magazine for health conscious consumers. Widely distributed to thousands of health-food stores and grocery chains across the country, Better Nutrition provides authoritative, well-researched information on food nutrition, dietary concerns, supplements and other natural products.
Olive Leaf Extract has been used with remarkable success against every infective
organism type—viral, bacterial, fungal, and protozoan (parasitic) infections. New
clinical experience shows that olive leaf extract is an effective treatment for an ...
Author: Sarah Abernathy
Publisher: Healthy Healing, Inc.
Category: Health & Fitness
Experience the journey of fertility, conception, pregnancy and birth, naturally! Millions of people struggle with fertility problems. Most can overcome them with simple lifestyle changes and natural therapies. Written by two experts in the field of Natural Health, "Do You Want to Have a Baby?" covers optimal nutrition for conception, the best fertility-enhancing supplements, and the documented success of bodywork therapies. The book also addresses the heartbreak of miscarriage and how to improve your chances if you are at risk. The book includes a step-by-step diet for nutritional demands during pregnancy with special suggestions for women expecting multiples. It provides detailed recommendations on herbs you can use safely during pregnancy and nursing, and what to avoid. An expanded section on the special problems of pregnancy reveals the best natural therapies to reduce fatigue, haemorrhoids, morning sickness, labour pain, stretch marks, swollen ankles and many other common complaints. The book also explains your options for labour and delivery, how to avoid unnecessary medical interventions, and even offers special recommendations for losing post-pregnancy weight. Look for the bonus section on natural baby care!
Antimicrobial activity of olive (Olea europaea) leaf extract to be used during the
elaboration process of green table olives T. ... The high content of oleuropein and
other phenolic compounds identified in the extract could contribute to its ...
Author: A. Méndez-Vilas
Microbes in the Spotlight: Recent Progress in the Understanding of Beneficial and Harmful Microorganisms contains a selection of papers presented at the VI International Conference on Environmental, Industrial and Applied Microbiology - BioMicroWorld2015 (Barcelona, Spain). This book offers the outcomes of completed and outgoing research works and experiences of several microbiology research groups across the world. The volume is divided into the following sections: --Agricultural and environmental microbiology. Biodeterioration, biodegratation, bioremediation --Food microbiology --Medical microbiology. Antimicrobial agents and chemotherapy. Antimicrobial resistance --Industrial microbiology. Microbial production of high-value products --Biotechnologically relevant enzymes and proteins --Methods and technology development --Microbial physiology Readers will find this book a useful opportunity to keep up with the latest research results, insights and advances in the microbiology field.
OLIVE LEAF EXTRACT • Olea europaea F A C T S The olive branch may be a
universal sign of peace , but the extract from the olive leaf is a potent fighter
against disease . Olive leaf contains a compound called oleuropein acid , a
Author: Earl Mindell
Publisher: Simon and Schuster
Category: Health & Fitness
The Bestselling Guide to Herbal Remedies -- Completely Revised and Expanded Since its original publication in 1992, Earl Mindell's Herb Bible has become the definitive guide to the world of herbal remedies. Recognized as today's leading trend in self-care, herbs can help you heal faster, live longer, and look better. In this completely updated edition, one of the world's foremost authorities on nutrition and natural remedies demystifies the language and lore of herbs, and shows you how to choose and use herbs and herbal treatments -- from the traditional favorites to those on the cutting edge. Here is new and valuable information on how herbs can treat depression and anxiety, boost energy, improve your sex life, combat aging, prevent illness, and speed healing. Highlights include: Thirty new "Hot Hundred" herbs A new section devoted specifically to anti-aging herbs New and completely updated information on the fastest selling herbs: St. John's wort, kava kava, grapeseed extract, and green tea Special updated chapters on "A Man's Body" and "A Woman's Body" And much more Commercially prepared yet free of synthetics, herbal remedies are now widely available in many forms, from teas to tinctures. Authoritative and easy to use, this comprehensive resource is an essential addition to every medicine chest.
Data from the parallel examination of olive leaf extract (25% oleuropein) and
pure compounds, namely, oleuropein (~90%), verbascoside, tyrosol,
hydroxytyrosol, luteolin 7-O-glucoside, and luteolin towards ABTS ̇ indicated the
superiority of ...
Author: Victor R. Preedy
Publisher: Academic Press
Category: Technology & Engineering
Long used in sacred ceremonies and associated with good health, the nutritional and health promoting benefits of olives and olive oils have been proven by an ever-increasing body of science. From cardiovascular benefits to anti-microbial, anti-cancer, antioxidant activity and effects on macrophages and aptoptosis to cellular and pathophysiollogical process, olives and olive oils are proving important in many healthful ways. For example, reactive components in olive oils or olive oil by-products have now been isolated and identified. These include tyrosol, hydroxytyrosol, 3,4-dihydroxyphenyl acetic acid elenolic acid and oleuropein. Oleic acid is the main monosaturated fatty acid of olive oil. These have putative protective effects and modulate the biochemistry of a variety of cell types including those of the vascular system. Some but not all components have been characterised by their putative pharmacological properties. It is possible that usage of these aforementioned products may have beneficial application in other disease. However, in order for this cross-fertilization to take place, a comprehensive understanding of olives and olive oils is required. Finding this knowledge in a single volume provides a key resource for scientists in a variety of food an nutritional roles. Key Features: * Explores olives and olive oil from their general aspects to the detailed level of important micro-and micronutrients * Includes coverage of various methodologies for analysis to help scientists and chemists determine the most appropriate option for their own studies, including those of olive-related compounds in other foods * Relates, in a single volume resource, information for food and nutritional chemists, pharmaceutical scientists, nutritionists and dieticians * Presents information in three key categories: General aspects of olives an olive oils; Nutritional, pharmacological and metabolic properties of olives and olive oil; Specific components of olive oil and their effects on tissue and body systems
Olive leaf extract also contains a variety of phenolic compounds, most importantly
oleuropein, hydroxytyrosol and tyrosol, and also rutin, luteolin, catechin and
apigenin, and various nutrients such as selenium, chromium, iron, zinc, vitamin C
Author: Lesley Braun
Publisher: Elsevier Health Sciences
A must-have health companion for herbalists, naturopaths, complementary medicine practitioners and students Herbs and Natural Supplements, 3rd Edition: An evidence-based guide presents evidence-based information on the 130 most popular herbs, nutrients and food supplements used across Australia and New Zealand. This exhaustive textbook is organised alphabetically by each herb or nutrient’s common name. Herbs and nutrients are then accompanied by critical information such as daily intake, main actions and indications, adverse reactions, contraindications and precautions, safety in pregnancy and more. This new edition of Herbs and Natural Supplements has been expanded with new chapters on pregnancy and wellness. It also features 10 new monographs for Arginine, Dunaliella, Elde, Goji, Pelargonium, Prebiotics, Red Yeast Rice, Rhodioloa, Shatavari and Taurine. • provides current, evidence-based information on herbal, nutritional and food supplements used in Australia and New Zealand • is user-friendly and easily organised by easy-to-find A-Z herbal monographs • appendices offering important additional information for the safe use of herbal and nutritional supplements, including a list of poison information centres, associations, manufacturers and more • offers clear, comprehensive tables including herb/natural supplement - drug interactions • lists the pharmacological actions of all herbs and natural supplements • a glossary of terms relevant to herbs and natural supplements • two comprehensive new chapters: Herbs and Natural Supplements in Pregnancy and Introduction to Wellness • all chapters completely updated and expanded • ten new monographs taking the total to 130 • now also available as an eBook! A code inside Herbs and Natural Supplements, 3rd Edition: An evidence-based guide enables a full text download, allowing you to browse and search electronically, make notes and bookmarks in the electronic files and highlight material
Olive leaf extract exhibited antihypertensive activity after oral administration in an
experimental model of hypertension.10 Oleuropein has been shown to reduce
blood pressure in both normotensive and hypertensive models after injection.11
Author: Kerry Bone
Publisher: Elsevier Health Sciences
This clinical guide and practical reference is ideal for those who use and combine liquid herbal remedies for the individual needs of the patient. With three introductory chapters, 125 monographs, and various glossaries and appendices, it covers the fundamental concepts of using liquid herbals, including how the remedies are made, quality issues, and dosage guidelines. The monographs include full prescribing information that covers actions, indications, contraindications, warnings and precautions, interactions, side effects, dosage, traditional usage, pharmacological research, clinical studies, and full references. Focuses solely on liquid herbal preparations — making it a must-have resource and the only book of its kind. Covers approximately 125 herb profiles in detail. Offers the widest range of research-backed information currently available on herbs. Begins with basic principles to give practitioners confidence in the accuracy and precision of their prescriptions. Written by one of the leading names in herbal medicine. Clinically relevant with quick access to dosage information, contraindications, and more.
The book includes the most up-to-date information from medical journals, scientific symposia, and other resources from around the world.
Author: Frank Murray
Publisher: McGraw Hill Professional
Category: Sports & Recreation
Although humans can't live forever, life can be prolonged by paying more attention to diet, lifestyle, exercise, and the supplements that are the cornerstone of today's modern medicine. 100 Super Supplements for a Longer Life highlights the many vitamins, minerals, herbs, amino acids, phytonutrients, and other natural substances that are being used to prevent and/or treat heart disease, stroke, cancer, high blood pressure, diabetes, Alzheimer's disease, aging, and other debilitating illnesses. The book includes the most up-to-date information from medical journals, scientific symposia, and other resources from around the world.
Olive leaf extract is known to help eradicate these viral problems.43 OLIVE LEAF EXTRACT AND HIV/AIDS The antiviral activity of oliveleaf extract is due to the
action of oleuropein on the protein coat of the virus. It is thought to inactivate ...
Author: Kathleen O'Bannon
Publisher: Thomas Nelson
Discover the World's Most Proven Health Plan You want to be healthy, but all those diet fads have left you hungry for something more. There's one Plan for healthy living that's guaranteed to satisfy and that's God's plan! With The Smart Guide to the Bible: Nutrition and Health in the Bible you'll get all your needs met: mind, body, and soul. You'll be amazed at the complete information the Bible contains about nutrition, health, exercise, weight loss, food, cooking, fasting, and remedies. And, of course, it all aligns with the latest in scientific research. No surprise there; after all, God designed the human body and knows what's best to keep it healthy! Get started on the world's most proven health plan today! Be Smart About: Weight Loss Eating to Combat Disease Exercise Fasting Biblical Diets Bible-based Recipes & Remedies Healthy Living for Your Family And More!
Olive oil and olive leaf extract (Olea europaea) can be used for hydration, for
wound healing, and to stimulate blood flow15. The oil is used for scars, cleansing
, calluses, brittle nails, onychomycosis, hair conditioning, sunburn and diaper ...
Author: Jean L. Bolognia
Publisher: Elsevier Health Sciences
Dermatology, edited by world authorities Jean L. Bolognia, MD, Joseph L. Jorizzo, MD, and Julie V. Schaffer, MD, is an all-encompassing medical reference book that puts the latest practices in dermatologic diagnosis and treatment at your fingertips. It delivers more comprehensive coverage of basic science, clinical practice, pediatric dermatology, and dermatologic surgery than you’ll find in any other source. Whether you’re a resident or an experienced practitioner, you’ll have the in-depth, expert, up-to-the-minute answers you need to overcome any challenge you face in practice. Find answers fast with a highly user-friendly, "easy-in-easy-out" format and a wealth of tables and algorithms for instant visual comprehension. Get full exposure to core knowledge with coverage of dermatology’s entire spectrum of subspecialties. See just the essential information with "need-to-know" basic science information and key references. Expedite decision making and clarify complex concepts with logical tables, digestible artwork, and easy-to-grasp schematics. Visualize more of the conditions you see in practice with over 3500 illustrations, of which over 1,400 are new: 1,039 clinical images, 398 pathology slides, and 152 schematics. Stay at the forefront of your field with updated treatment methods throughout, as well as an increased focus on patients with skin of color. Get an enhanced understanding of the foundations of dermatology in pathology, the clinical setting, and dermoscopy with a completely rewritten introductory chapter. Better comprehend the clinical-pathological relationship of skin disease with increased histologic coverage. Bolognia’s Dermatology is the ultimate multimedia reference for residents in training AND the experienced practitioner.
Release on 2009-01-01 | by Ioannis Nikolaos Therios
OLEUROPEIN Oleuropein as an antioxidant Oleuropein is the bitter compound of olives that enhances nitric oxide ... This is commonly found in the Mediterranean
diet, which is rich in fresh fruits, vegetables and olive oil and has been ...
Author: Ioannis Nikolaos Therios
Category: Technology & Engineering
Olives are not only a significant food source, but also contribute to human health and are popular in health-conscious diets far beyond their Mediterranean origins. This guide deals with various aspects of olive culture, from its history, origins and traditional techniques to horticultural procedures and basic physiology.
Olive Leaf Extract Made from the leaves of olive trees, this extract contains
oleuropein, a powerful polyphenol with anti-inflammatory properties that
stimulates the immune system and reduces abdominal bloating and gas. Olive leaf extract also ...
Author: Haylie Pomroy
Category: Health & Fitness
In the #1 New York Times bestseller The Fast Metabolism Diet, powerhouse nutritionist Haylie Pomroy showed readers how to heal a broken metabolism with the strategic use of macronutrients. But even in the best running systems, inflammation, digestive dysfunction, and hormonal imbalances can all hinder weight-loss. In The Burn, Haylie breaks new ground and gives anyone trying to lose weight new tools for busting through plateaus. Using targeted micronutrients to incinerate weight-loss roadblocks, Haylie will help you remove the problem—and lose up to 3, 5, and 10 pounds in as many days! The Burn offers three eating plans, therapeutically designed to achieve highly specific results. The I-Burn targets the body’s inflammatory reactions to food and flushes out toxins and subcutaneous fat, producing prominent cheekbones and a glowing complexion in three days. In five days, the D-Burn unblocks the body’s digestive barrier and torches torso fat, to create a flat belly and tighter waistline. The 10-day H-Burn addresses the hormonal system, repairing and facilitating the proper synthesis of hormones to reshape lumps and bumps into gorgeous curves, sleeker hips, and thinner thighs. The Burn also unveils: · I-Burn, D-Burn, and H-Burn eating and living plans, complete with detailed grocery lists and daily menus to keep the process simple and easy-to-follow. · Dozens of delicious recipes for meals in a flash. · Simple success boosters: foods, teas, tips, and practices that are easy to incorporate and stoke up your body’s ability to heal. · How to live your life on fire – road maps that help readers recognize what their bodies are saying to keep their metabolisms blazing! From the Hardcover edition.