Teratocarcinoma Stem Cells

Teratocarcinoma Stem Cells


Teratocarcinoma Stem Cells

When EC cells are injected into the blastocyst, the hope is that the embryonic environment will induce the pluripotent stem cells to revert to their embryonic fate and undergo normal differentiation, with concomitant loss of stem cell ...

Teratocarcinoma Stem Cells


Human Embryonic Stem Cells

In Human Embryonic Stem Cells, pioneers, leaders, and experts in this emerging field join forces to address all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from ...

Human Embryonic Stem Cells

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Differing Routes to Stem Cell Research

Ethical concerns prevailed. The present volume follows the controversial discussions on stem cells in Italy and Germany, respectively, over the past 15 years. It aims at an assessment of the situation, and its method is comparative.

Differing Routes to Stem Cell Research

Stem cells have been in the center of a heated biomedical and biopolitical debate in the first decade of the new millennium. Ethical concerns prevailed. The present volume follows the controversial discussions on stem cells in Italy and Germany, respectively, over the past 15 years. It aims at an assessment of the situation, and its method is comparative. The first part of the book takes a step back and sheds light on the early history of views on stem cells and on cellular reprogramming from the middle of the nineteenth to the end of the twentieth century. Part two and three have a close look on the recent developments in Germany and in Italy from three different viewpoints: the state of the art in scientific research, the public debate on its perceived promises and dangers, and the political and legal regulations that followed. It turns out that, despite their cultural and geographical vicinity, there are significant national differences in the discursive and juridical strategies followed in both European countries.

Pluripotent Stem Cells

This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing ...

Pluripotent Stem Cells

Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.

Atlas of Human Pluripotent Stem Cells

The Atlas of Human Pluripotent Stem Cells - Derivation and Culturing will serve as a reference and guide to established researchers and those wishing to enter the promising field of pluripotent stem cell research.

Atlas of Human Pluripotent Stem Cells

Human pluripotent stem cells, including human embryonic stem cells and induced pluripotent stem cells, are a key focus of current biomedical research. The emergence of state of the art culturing techniques is promoting the realization of the full potential of pluripotent stem cells in basic and translational research and in cell-based therapies. This comprehensive and authoritative atlas summarizes more than a decade of experience accumulated by a leading research team in this field. Hands-on step-by-step guidance for the derivation and culturing of human pluripotent stem cells in defined conditions (animal product-free, serum-free, feeder-free) and in non-adhesion suspension culture are provided, as well as methods for examining pluripotency (embryoid body and teratoma formation) and karyotype stability. The Atlas of Human Pluripotent Stem Cells - Derivation and Culturing will serve as a reference and guide to established researchers and those wishing to enter the promising field of pluripotent stem cells.