Veterinary Pharmacovigilance

This book will be fundamentally important reading for all involved in the field of veterinary pharmacovigilance including veterinarians, physicians, environmental scientists, regulators and those involved in drug development and market ...

Veterinary Pharmacovigilance

Veterinary Pharmacovigilance: Adverse Reactions to Veterinary Medicinal Products is an in-depth examination of veterinary pharmacovigilance, looking at the scientific methodologies involved, the role of regulatory agencies and legislation, and the underpinning science. Edited by a renowned expert with over 20 years of experience in the field, it draws together the expertise of authors from around the world.

Toxicological Effects of Veterinary Medicinal Products in Humans

K. N. Woodward, Regulation of veterinary drugs in General and Applied Toxicology, ed. B. Ballantyne, T. Marrs and T. Syversen, Macmillan, Basingstoke, 2nd edn, 2000, pp. 1633–1652. K. N. Woodward, Veterinary pharmacovigilance. Part 1.

Toxicological Effects of Veterinary Medicinal Products in Humans

Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans. The chapters focus on occupational safety and consumer issues and examine the circumstances under which exposure is likely to occur. To be in context, it reviews this against the background of adverse health effects from other sources in the veterinary and farming professions. The book examines adverse drug effects reported to regulatory agencies (mainly the FDAAEs Center for Veterinary Medicine) and then considers a series of individual drugs, including antibiotics, anaesthetics and organophosphorus compounds. The chapters also discuss the fundamental aspects of regulatory issues relating to safety assessment, and examine the manner in which user safety is assessed prior to authorisation/approval and what measures can be taken after authorisation/approval in the light of findings from pharmacovigilance activities. There is growing concern over the issue of antimicrobial resistance and the contribution made by veterinary medicinal products. This too is addressed along with the significance to human health and measures that can be taken to mitigate the effects (if any) of the use of antibiotics in animals e.g. prudent use measures. The book will be an essential resource for medical practitioners in hospitals and general practice, pharmaceutical industry scientists, analysts, regulators and risk managers."

Veterinary Toxicology

Veterinary pharmacovigilance within the federal government is typically based on the receipt of spontaneous reports involving complaints of product performance. Spontaneous refers to reports that are voluntarily submitted by ...

Veterinary Toxicology

Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology

Toxicological Effects of Veterinary Medicinal Products in Humans

K. N. Woodward, Veterinary pharmacovigilance in the European Union, in Veterinary Pharmacovigilance. Adverse Reactions to Veterinary Medicinal Products, ed. K. N. Woodward, Wiley-Blackwell, Chichester, 2009, pp. 19–46.

Toxicological Effects of Veterinary Medicinal Products in Humans

Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans. The chapters focus on occupational safety and consumer issues and examine the circumstances under which exposure is likely to occur. To be in context, it reviews this against the background of adverse health effects from other sources in the veterinary and farming professions. The book examines adverse drug effects reported to regulatory agencies (mainly the FDAAEs Center for Veterinary Medicine) and then considers a series of individual drugs, including antibiotics, anaesthetics and organophosphorus compounds. The chapters also discuss the fundamental aspects of regulatory issues relating to safety assessment, and examine the manner in which user safety is assessed prior to authorisation/approval and what measures can be taken after authorisation/approval in the light of findings from pharmacovigilance activities. There is growing concern over the issue of antimicrobial resistance and the contribution made by veterinary medicinal products. This too is addressed along with the significance to human health and measures that can be taken to mitigate the effects (if any) of the use of antibiotics in animals e.g. prudent use measures. The book will be an essential resource for medical practitioners in hospitals and general practice, pharmaceutical industry scientists, analysts, regulators and risk managers."

Regulatory Toxicology in the European Union

Committee for veterinary Medicinal products, EMEA Public Bulletin 2005 on Veterinary Pharmacovigilance. EMEA/CVMP/226674/2005, available at: http://www.ema.europa.eu/docs/en_GB/document_library/ other/2009/10/WC500004964.pdf, ...

Regulatory Toxicology in the European Union

Consumer and environmental protection depend on the careful regulation of all classes of chemicals. Toxicology is the key science used to evaluate safety and so underpins regulatory decisions on chemicals. With the growing body of EU legislation involved in chemical regulation, there is a concomitant need to understand the toxicological principles underlying safety assessments Regulatory Toxicology in the European Union is the first book to cover regulatory toxicology specifically in Europe. It addresses the need for a wider understanding of the principles of regulatory toxicology and their application and presents the relationship between toxicology and legislative processes in regulating chemical commodities across Europe. This title has a broad scope, covering historical and current chemical regulation in Europe, the role of European agencies and institutions, and also the use of toxicology data for important classes of chemicals, including human and veterinary medicines, animal feed and food additives, biocides, pesticides and nanomaterials. This book is therefore extremely pertinent and timely in the toxicology field at present. This book is an essential reference for regulatory authorities, industrialists, academics, undergraduates and postgraduates working within safety and hazards, toxicology, the biological sciences, and the medicinal and pharmaceutical sciences across the European Union.

Blackwell s Five Minute Veterinary Practice Management Consult

Elements of veterinary pharmacovigilance, K.N. Woodward, Veterinary Pharmacovigilance: Adverse Reactions to Veterinary Medicinal Products, Woodward, K., Ed. Wiley-Blackwell 2009, pp. 9– 10. 5. www.usp.org/about-usp.

Blackwell s Five Minute Veterinary Practice Management Consult

Blackwell’s Five-Minute Veterinary Practice ManagementConsult, Second Edition has been extensively updated andexpanded, with 55 new topics covering subjects such as onlinetechnologies, hospice care, mobile practices, compassion fatigue,practice profitability, and more. Carefully formatted using thepopular Five-Minute Veterinary Consult style, the bookoffers fast access to authoritative information on all aspects ofpractice management. This Second Edition is an essential tool forrunning a practice, increasing revenue, and managing staff intoday’s veterinary practice. Addressing topics ranging from client communication andmanagement to legal issues, financial management, and humanresources, the book is an invaluable resource for businessmanagement advice applicable to veterinary practice. Sample formsand further resources are now available on a companion website.Veterinarians and practice managers alike will find this book acomprehensive yet user-friendly guide for success in today’schallenging business environment.

Veterinary Pharmacology and Therapeutics

Although CVM was exempt from the Sentinel Initiative, the use of sentinel surveillance methods are of interest in the field of veterinary pharmacovigilance. CVM completed a project investigating the current electronic data sources that ...

Veterinary Pharmacology and Therapeutics

Veterinary Pharmacology and Therapeutics, Tenth Edition is a fully updated and revised version of the gold-standard reference on the use of drug therapy in all major veterinary species. Provides current, detailed information on using drug therapies in all major domestic animal species Organized logically by drug class and treatment indication, with exhaustive information on the rational use of drugs in veterinary medicine Includes extensive tables of pharmacokinetic data, products available, and dosage regimens Adds new chapters on pharmaceutics, ophthalmic pharmacology, food animal pharmacology, and aquatic animal pharmacology Includes access to a companion website with the figures from the book in PowerPoint

Toxicological Effects of Veterinary Medicinal Products in Humans

Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans.

Toxicological Effects of Veterinary Medicinal Products in Humans

Toxicological Effects of Veterinary Medicinal Products in Humans is the first definitive guide to discuss the adverse effects of veterinary medicinal products in humans. The chapters focus on occupational safety and consumer issues and examine the circumstances under which exposure is likely to occur. To be in context, it reviews this against the background of adverse health effects from other sources in the veterinary and farming professions. The book examines adverse drug effects reported to regulatory agencies (mainly the FDAÆs Center for Veterinary Medicine) and then considers a series of individual drugs, including antibiotics, anaesthetics and organophosphorus compounds. The chapters also discuss the fundamental aspects of regulatory issues relating to safety assessment, and examine the manner in which user safety is assessed prior to authorisation/approval and what measures can be taken after authorisation/approval in the light of findings from pharmacovigilance activities. There is growing concern over the issue of antimicrobial resistance and the contribution made by veterinary medicinal products. This too is addressed along with the significance to human health and measures that can be taken to mitigate the effects (if any) of the use of antibiotics in animals e.g. prudent use measures. The book will be an essential resource for medical practitioners in hospitals and general practice, pharmaceutical industry scientists, analysts, regulators and risk managers.

Diseases of Sheep

World Health Organization (2002) The Importance of Pharmacovigilance. Safety Monitoring of Medicinal Products. WHO, Geneva. Keck, G. and Ibrahim, C. (2001) Veterinary pharmacovigilance: between regulation and science.

Diseases of Sheep

First published in 1983, Diseases of Sheep has become a definitive reference book on sheep diseases. This new edition has been revised and updated to maintain its original core structure and its international approach to the many diseases which affect sheep. Any veterinary surgeon or agriculturalist who works with sheep will continue to find the information in this book the most authoritative and comprehensive available. Known to many as the "Moredun Sheep Book" because of its association with the Moredun Research Institute, long recognised as a centre of excellence in sheep disease research. Special attention is given to specific regional disease problems in the Middle East, Southern Africa, Australia, New Zealand, North America and South America. Covers technical aspects of disease prevention and treatment, including uncommon diseases, as well as sheep welfare issues.

Mammalian Toxicology of Insecticides

K. Chung, C.-C. Yang, M.-L. Wu, J.-F. Deng and W.-J. Tsai, Agricultural avermectins: an uncommon but potentially fatal cause of pesticide poisoning, Ann. Emerg. Med., 1999, 34, 51–57. K. N. Woodward, Veterinary pharmacovigilance.

Mammalian Toxicology of Insecticides

Insects are more similar in structure and physiology to mammals than plants or fungi. Consequently, insecticides are often of greater toxicity to mammals than herbicides. This is particularly the case with neurotoxins. However, some insecticides are targeted at structures or hormonal systems specific to insects (insect growth regulators/chitin synthesis inhibitors) so are less harmful but can still be mildly haematotoxic. There are, therefore, issues specific to insecticides, which do not occur with other pesticides - hence the need for a book specifically on insecticide toxicology in mammals. The book starts with general issues relating to the mammalian toxicity of insecticides, including target/non-target specificity, nomenclature and metabolism of insecticides. It then goes on to discuss specific types of insecticides including: organochlorines; anticholinesterases; pyrethrum and synthetic pyrethroids; nicotine and the neonicotinoids; insect growth regulators/ecdysone agonists/chitin synthesis inhibitors; insecticides of natural origin; biological insecticides; and insecticides used in veterinary medicine.

Clinical Veterinary Toxicology E Book

Veterinary pharmacovigilance within the federal government is typically based on the receipt of spontaneous reports involving complaints of product performance. Spontaneous refers to reports that are voluntarily submitted by ...

Clinical Veterinary Toxicology   E Book

This book covers all aspects of toxicology, including toxic diseases of large animals, small animals, and exotic pets. It provides key information on how poisons affect the body, how the body responds to a foreign substance, how poisonings are diagnosed, and how poisonings are treated. Coverage includes every organ system of every species of animal with details on each body system's susceptibility to poison. Poisons affect animals differently depending on species, breed, age, gender, health status, and reproductive status. This resource addresses these differences, allowing the veterinarian to determine the class of toxicant, the mechanism of action, and the proper course of treatment. If confronted with an unknown poison, the information in this book will assist the veterinarian in formulating a list of potential poisons based on the clinical signs that the animal is exhibiting, and in choosing the appropriate tests to narrow the list to one or a few possible poisons. Most comprehensive toxicology book available Written in a user-friendly style that makes it easy to master the content Covers poisonings in both large and small domestic animals The Principles of Toxicology section provides comprehensive coverage of concepts & terminology, toxicokinetics, treatments, and regulatory information The Manifestations of Toxicoses section is devoted to differentiating between poisons based on lesions and clinical signs The Classes of Toxicants section offers detailed information on each poison, including sources, risk factors, pathophysiology, clinical signs and lesions, diagnostic testing, and treatment The author is board-certified in toxicology, and the contributors are all toxicologists and educators, ensuring authoritative, up-to-date clinical information

Kirk s Current Veterinary Therapy XIV E Book

The purpose of pharmacovigilance is to give some assurance that the animal drug labeling is accurate beyond the initial product launch. One ADE report does not provide enough information for a label change. A reliable safety profile ...

Kirk s Current Veterinary Therapy XIV   E Book

From medical disorders to toxicology to infectious disease, Kirk’s Current Veterinary Therapy XIV includes the most up-to-date information from leading experts in the veterinary field with over 260 new chapters. The user-friendly format presents content clearly to help you easily find the information you need and put it in practice. Selective lists of references and suggested readings provide opportunities for further research, and the Companion CD includes helpful information from the previous volume that still applies to current practice. Authoritative, reliable information on diagnosis includes details on the latest therapies. An organ-system organization makes it easy to find solutions for specific disorders. Concise chapters are only 2-5 pages in length, saving you time in finding essential information. Well-known writers and editors provide accurate, up-to-date coverage of important topics. A convenient Table of Common Drugs, updated by Dr. Mark Papich, offers a quick reference to dosage information. Cross-references to the previous edition make it easy to find related information that remains valid and current. A list of references and suggested readings is included at the end of most chapters. A fully searchable companion Evolve website adds chapters from Kirk’s Current Veterinary Therapy XIII, with information that has not changed significantly since its publication. It also includes an image collection with over 300 images, and references linked to PubMed. Useful appendices on the website provide a virtual library of valuable clinical references on laboratory test procedures and interpretation, normal reference ranges, body fluid analyses, conversion tables, nutritional profiles, a drug formulary, and more. More than 260 new chapters keep you at the leading edge of veterinary therapy.

Drug Delivery Trends

2.6.3 Committee for medicinal products for veterinary use [8] This is the EMA's committee responsible for veterinary medicines, established in line with Regulation (EC) No. 726/2004. 2.6.2 Pharmacovigilance risk assessment committee [7] ...

Drug Delivery Trends

Drug Delivery Trends examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This volume additionally covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems. Encompasses trends in drug delivery systems and selected dosage forms Illustrates regulatory, preclinical and quality principles Contains in-depth investigation of upcoming types of drug delivery systems

Therapeutics and Control of Sheep and Goat Diseases An Issue of Veterinary Clinics Food Animal Practice E Book

Naidoo V, Sykes R. Overview of suspected adverse reactions to veterinary medicinal products reported in South Africa (March 2004–February 2006). JS Afr Vet Assoc 2006;77:164–7. Woodward KN. Veterinary pharmacovigilance. Part 1.

Therapeutics and Control of Sheep and Goat Diseases  An Issue of Veterinary Clinics  Food Animal Practice   E Book

A comprehensive review of therapeutics and control of sheep and goat diseases for the food animal practitioner! Topics include pharmaceutical control of reproduction in sheep and goats, drug laws and regulations in sheep and goats, treatment and control of peri-parturient metabolic diseases in sheep and goats, treatment and control of mastitis and contagious agalactia, control of important clostridial diseases of sheep, treatment and control of ectoparasites in small ruminants, treatment and control of respiratory disease in sheep, treatment of emergency conditions in sheep and goat, control of brucella ovis infection in sheep, non-pharmaceutical control of endoparasitic infections of sheep, anaesthesia and analgesia in sheep and goats, control of paratuberculosis in sheep and goats, pharmaceutical control of endoparasitic infections in sheep, treatment and control of hoof disorders in sheep and goats, and much more!

Kirk s Current Veterinary Therapy XV E Book

Available at: http://www.aphis.usda.gov/animal_ health/vet_biologics/vb_adverse_event.shtml. Accessed April 10, 2012. Woodward KN, editor: Veterinary pharmacovigilance: adverse reactions to veterinary medicinal products, West Sussex, ...

Kirk s Current Veterinary Therapy XV   E Book

Written by today s leading experts, Kirk's Current Veterinary Therapy, Volume XV keeps you completely current with the latest in disease management for dogs and cats. It uses a clear and practical approach to medical disorders; the typical chapter includes both a brief guide to diagnosis and a detailed discussion of therapy. You ll gain quick access to information such as critical care; infectious, toxicologic, and dermatologic disorders; and diseases of the gastrointestinal, cardiovascular, respiratory, urinary, reproductive, neurologic,and ophthalmologic systems. From editors John Bonagura and David Twedt plus hundreds of expert contributors, Kirk's Current Veterinary Therapy enhances your skills in evidence-based treatment planning. "For the practitioner who wants to keep abreast of current therapies for a wide range of topics, ... CVT is the perfect reference ." Reviewed by: Ryan Ong, WAVES Veterinary Hospital on behalf of Australian Veterinary Hospital, March 2015 Authoritative, easy-to-read coverage includes a brief approach to diagnosis with detailed discussions of the latest therapies. An organ-system organization and a convenient index make it easy to find solutions for specific disorders. Treatment algorithms help you manage patients with difficult medical problems. A handy Table of Common Drugs, updated by Dr. Mark Papich, offers a quick reference to dosage information. 365 illustrations depict the pathophysiologic basis for therapy or show the management of a defined condition. A companion website includes valuable information still relevant from CVT XIV, an index, and drug formulary, all fully searchable; a collection of 300 images; references that link to PubMed; and clinical references on laboratory test procedures and interpretation, normal reference ranges, conversion tables, and more. Concise chapters are only 2-5 pages in length, saving you time in finding essential information. Expert contributors and editors provide scientific, up-to-date coverage of clinically useful topics, including broad, traditional, and controversial subjects. References indicate related material from earlier volumes of Kirk’s Current Veterinary Therapy. NEW chapters cover the most important, emerging information on current diagnostic, treatment, and preventive challenges in today’s veterinary practice. A new section on feline and canine nutrition covers important issues in nutritional health. 50 new chapter authors join hundreds of expert international contributors, all of whom are leading authorities in their fields. NEW! Availability as Pageburst ebook allows you digital access to this volume along with your library of other Elsevier references.

Improving Farmed Fish Quality and Safety

WOODWARD K N (2005a), `Veterinary pharmacovigilance Part 2. Veterinary pharmacovigilance in practice ± the operation of a spontaneous reporting scheme in a European Union country ± the UK, and schemes in other countries', J Vet Phamacol ...

Improving Farmed Fish Quality and Safety

Global aquaculture production has grown rapidly over the last 50 years. It is generally accepted that there is limited potential to increase traditional fisheries since most fish stocks are well or fully exploited. Consequently increased aquaculture production is required in order to maintain global per capita fish consumption at the present level. Fish farming enables greater control of product quality and safety, and presents the possibility of tailoring products according to consumer demands. This important collection reviews safety and quality issues in farmed fish and presents methods to improve product characteristics. The first part of the book focuses on chemical contaminants, chemical use in aquaculture and farmed fish safety. After an opening chapter discussing the risks and benefits of consumption of farmed fish, subsequent contributions consider environmental contaminants, pesticides, drug use and antibiotic resistance in aquaculture. Part two addresses important quality issues, such as selective breeding to improve flesh quality, the effects of dietary factors including alternative lipids and proteins sources on eating quality, microbial safety of farmed products, parasites, flesh colouration and off-flavours. Welfare issues and the ethical quality of farmed products are also covered. The final part discusses ways of managing of product quality, with chapters on HACCP, monitoring and surveillance, authenticity and product labelling. With its distinguished editor and international team of contributors, Improving farmed fish quality and safety is a standard reference for aquaculture industry professionals and academics in the field. Reviews safety and quality issues in farmed fish and presents methods to improve product characteristics Discusses contaminants, persistent organic pollutants and veterinary drug residues and methods for their reduction and control Addresses important quality issues, genetic control of flesh characteristics and the effects of feed on product nutritional and sensory quality

Agricultural Medicine

Veterinary pharmacovigilance. Part 4. Adverse reactions in humans to veterinary medicinal products. J Vet Pharmacol Ther. 2005; 28(2):185–201. 16. Woodward K. Adverse reactions in humans follow- ing exposure to veterinary drugs.

Agricultural Medicine

Newly updated, Agricultural Medicine: Rural Occupational Health, Safety, and Prevention, Second Editionis a groundbreaking and comprehensive textbook and reference for students and practitioners of public health, and professionals in the field of rural agricultural occupational health and safety. The book introduces specific occupational and environmental health and safety issues faced by agricultural workers and rural residents, and provides a roadmap to establishing sustainable worker and public health support in agricultural communities. Responding to reader demand, Agricultural Medicine, Second Edition now features more case studies, key point summaries, and new international perspective chapters comparing North American health and agricultural practices to those in Europe, the Asia Pacific, and South America. Agricultural health and safety engages a multidisciplinary team of medical professionals, veterinarians, safety professionals, engineers, sociologists, epidemiologists, and psychologists, for whom this book serves as an essential resource.